Investigating development of infective stage larvae of filarial nematodes.
نویسنده
چکیده
Lymphatic filariasis is a parasitic disease affecting millions of individuals and one of the leading causes of disability in the world. However, considering the magnitude of filariasis as a public health problem, relatively little is known about the basic biology of the disease and its causative agents, filarial nematodes. In this paper, the biology of the infective stage larvae of the nematodes responsible for lymphatic filariasis and the approaches used to study their development are reviewed.
منابع مشابه
Expression and secretion of a larval-specific chitinase (family 18 glycosyl hydrolase) by the infective stages of the parasitic nematode, Onchocerca volvulus.
A recently reported chitinase gene, expressed in the infective, third-stage (L3) larvae of the human filarial parasite Onchocerca volvulus, belongs to the family 18 glycosyl hydrolases and has been designated Ov-chi-1. The gene product of Ov-chi-1 is chitinolytic. Allosamidin ablates activity of the native enzyme in a dose-dependent manner but did not significantly inhibit the moulting of L3 la...
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ورودعنوان ژورنال:
- Frontiers in bioscience : a journal and virtual library
دوره 5 شماره
صفحات -
تاریخ انتشار 2000